HitPredict

Interactor 1: DESM (P17661)
Desmin
Gene: DES

Interactor 2: NEBU (P20929)
Nebulin
Gene: NEB

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	11309420
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0030018 - Z disc GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 470 Hs			1 8525
+	Hs
		443328 VIME_HUMAN (28-469): 1.16e-150: 439: 62.19		NEBU_HUMAN (1-8525): 0: 8652: 100.00
+	Hs
		443504 VIME_HUMAN (28-469): 1.16e-150: 439: 62.19		SPTN1_HUMAN (7876-8525): 2.1e-58: 229: 11.33
+	Hs
		535403 GFAP_HUMAN (89-470): 3.61e-131: 387: 61.62		ITSN1_HUMAN (7577-8524): 1.01e-46: 190: 11.23
+	Hs
		443774 VIME_HUMAN (28-469): 1.16e-150: 439: 62.19		SRBS1_HUMAN (8368-8525): 5.41e-27: 125: 20.23
+	Hs
		569077 DESM_HUMAN (1-470): 3.6e-109: 333: 100.00		SPTN1_HUMAN (7876-8525): 2.1e-58: 229: 11.33
+	Hs
		443514 VIME_HUMAN (28-469): 1.16e-150: 439: 62.19		SRC8_HUMAN (8096-8488): 8.57e-18: 93.5: 11.51
+	Hs
		569085 DESM_HUMAN (1-470): 3.6e-109: 333: 100.00		ITSN1_HUMAN (7577-8524): 1.01e-46: 190: 11.23
+	Hs
		781978 PERI_HUMAN (12-470): 2.13e-134: 397: 59.14		SRBS1_HUMAN (8368-8525): 5.41e-27: 125: 20.23
+	Hs
		422175 NFL_HUMAN (87-418): 9.76e-89: 282: 53.89		SPTN1_HUMAN (7876-8525): 2.1e-58: 229: 11.33
+	Hs
		443521 VIME_HUMAN (28-469): 1.16e-150: 439: 62.19		LASP1_HUMAN (5895-6038): 2.35e-10: 67.3: 18.06
+	Hs
		282302 GFAP_HUMAN (89-470): 3.61e-131: 387: 61.62		NEBL_HUMAN (7761-8471): 8.74e-21: 104: 19.46
+	Hs
		422187 NFL_HUMAN (87-418): 9.76e-89: 282: 53.89		ITSN1_HUMAN (7577-8524): 1.01e-46: 190: 11.23
+	Hs
		781893 PERI_HUMAN (12-470): 2.13e-134: 397: 59.14		LASP1_HUMAN (5895-6038): 2.35e-10: 67.3: 18.06
+	Hs
		535397 GFAP_HUMAN (89-470): 3.61e-131: 387: 61.62		LASP1_HUMAN (5895-6038): 2.35e-10: 67.3: 18.06
+	Hs
		422404 NFM_HUMAN (100-417): 8.9e-78: 262: 46.42		ITSN1_HUMAN (7577-8524): 1.01e-46: 190: 11.23
+	Hs
		282299 NFL_HUMAN (87-418): 9.76e-89: 282: 53.89		NEBL_HUMAN (7761-8471): 8.74e-21: 104: 19.46
+	Hs
		422392 NFM_HUMAN (100-417): 8.9e-78: 262: 46.42		SRC8_HUMAN (8096-8488): 8.57e-18: 93.5: 11.51
+	Hs
		422179 NFL_HUMAN (87-418): 9.76e-89: 282: 53.89		LASP1_HUMAN (5895-6038): 2.35e-10: 67.3: 18.06