HitPredict

Interactor 1: PTPRF (A2A8L5)
Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR)
Gene: PTPRF

Interactor 2: CTNB1 (Q02248)
Catenin beta-1 (Beta-catenin)
Gene: Ctnnb1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	8830779
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008285 - negative regulation of cell population proliferation GO:0043065 - positive regulation of apoptotic process GO:0043525 - positive regulation of neuron apoptotic process GO:0044877 - protein-containing complex binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1898 Mm			1 781
+	Rn
		1145481 PTPRF_RAT (1-1898): 0: 1680: 98.63		CTNB1_RAT (1-781): 0: 650: 99.87
+	Hs
		489914 PTPRF_HUMAN (1-1898): 0: 1654: 95.39		CTNB1_HUMAN (1-781): 0: 650: 99.87
+	Hs
		489895 PTPRF_HUMAN (1-1898): 0: 1654: 95.39		PLAK_HUMAN (7-755): 1.54e-159: 482: 66.89
+	Hs
		576992 PTPRA_HUMAN (1105-1898): 0: 802: 40.05		CTNB1_HUMAN (1-781): 0: 650: 99.87
+	Hs
		617080 PTPRG_HUMAN (903-1895): 0: 747: 27.66		CTNB1_HUMAN (1-781): 0: 650: 99.87
+	Hs
		717036 PTPRJ_HUMAN (585-1895): 2.53e-136: 462: 18.76		CTNB1_HUMAN (1-781): 0: 650: 99.87
+	Hs
		542300 PTPRJ_HUMAN (585-1895): 2.53e-136: 462: 18.76		PLAK_HUMAN (7-755): 1.54e-159: 482: 66.89
+	Hs
		617157 PTPRZ_HUMAN (1126-1614): 3.2e-48: 192: 18.45		CTNB1_HUMAN (1-781): 0: 650: 99.87
+	Hs
		616904 PTPRB_HUMAN (392-1394): 5.31e-38: 159: 14.00		CTNB1_HUMAN (1-781): 0: 650: 99.87
+	Hs
		717099 PTPRK_HUMAN (208-772): 1.6e-31: 137: 17.71		CTNB1_HUMAN (1-781): 0: 650: 99.87
+	Mm
		472764 PTPRQ_MOUSE (764-1303): 1.38e-25: 118: 13.41		CTNB1_MOUSE (1-781): 0: 649: 100.00
+	Hs
		717247 PTPRU_HUMAN (363-747): 3.85e-17: 90.4: 16.17		CTNB1_HUMAN (1-781): 0: 650: 99.87
+	Hs
		441183 PTPRC_HUMAN (390-903): 5.95e-12: 73.5: 13.65		CTNB1_HUMAN (1-781): 0: 650: 99.87
+	Mm
		660881 PTPRM_MOUSE (125-534): 1.48e-10: 68.8: 16.44		CTNB1_MOUSE (1-781): 0: 649: 100.00
+	Dm
		578796 Q9W4F5_DROME (432-1412): 3.4e-46: 185: 14.38		ARM_DROME (25-780): 2.58e-163: 495: 67.00
+	Dm
		90970 E1JJE4_DROME (432-1412): 5.82e-46: 185: 14.38		ARM_DROME (25-780): 2.58e-163: 495: 67.00
+	Hs
		542330 PTPRK_HUMAN (208-772): 1.6e-31: 137: 17.71		PLAK_HUMAN (7-755): 1.54e-159: 482: 66.89
+	Mm
		472765 PTPRQ_MOUSE (764-1303): 1.38e-25: 118: 13.41		PLAK_MOUSE (7-755): 3.79e-158: 479: 66.62
+	Dm
		561758 PTP69_DROME (44-579): 3.9e-15: 83.9: 13.33		ARM_DROME (25-780): 2.58e-163: 495: 67.00