HitPredict

Interactor 1: DESM (P17661)
Desmin
Gene: DES

Interactor 2: DUX5 (Q96PT3)
Double homeobox protein 5
Gene: DUX5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.527

Property	Details
Experiments	26816005
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 470 Hs			1 197
+	Hs
		443864 VIME_HUMAN (28-469): 1.16e-150: 439: 62.19		DUX4_HUMAN (28-197): 4.94e-36: 132: 81.77
+	Hs
		408992 K2C8_HUMAN (81-464): 2.16e-139: 410: 35.01		PO2F1_HUMAN (7-180): 2.48e-31: 121: 17.13
+	Hs
		156121 PERI_HUMAN (12-470): 2.13e-134: 397: 59.14		PHX2A_HUMAN (1-127): 9.9e-16: 75.1: 27.69
+	Hs
		215071 DESM_HUMAN (1-470): 3.6e-109: 333: 100.00		DUX1_HUMAN (28-197): 2.64e-39: 134: 100.00
+	Hs
		1121887 Q53SB5_HUMAN (1-470): 3.6e-109: 333: 100.00		DUX4_HUMAN (28-197): 4.94e-36: 132: 81.77
+	Hs
		569132 DESM_HUMAN (1-470): 3.6e-109: 333: 100.00		DUX4_HUMAN (28-197): 4.94e-36: 132: 81.77
+	Hs
		569094 DESM_HUMAN (1-470): 3.6e-109: 333: 100.00		DUX4C_HUMAN (28-197): 3.72e-36: 131: 81.77
+	Hs
		829850 KRT81_HUMAN (1-416): 4.82e-90: 284: 30.95		HXA1_HUMAN (10-194): 3.1e-30: 114: 17.20
+	Hs
		829822 KRT83_HUMAN (8-423): 4.02e-89: 282: 30.48		HXA1_HUMAN (10-194): 3.1e-30: 114: 17.20
+	Hs
		422129 NFL_HUMAN (87-418): 9.76e-89: 282: 53.89		HXB5_HUMAN (7-193): 1.11e-29: 112: 18.56
+	Hs
		830038 KRT82_HUMAN (2-416): 3.17e-88: 280: 33.49		HXA1_HUMAN (10-194): 3.1e-30: 114: 17.20
+	Hs
		686437 KRT81_HUMAN (1-416): 4.82e-90: 284: 30.95		OTX1_HUMAN (26-120): 1.22e-13: 70.1: 35.79
+	Hs
		686429 KRT83_HUMAN (8-423): 4.02e-89: 282: 30.48		OTX1_HUMAN (26-120): 1.22e-13: 70.1: 35.79
+	Hs
		829960 KRT35_HUMAN (9-422): 1.39e-72: 238: 27.10		HXA1_HUMAN (10-194): 3.1e-30: 114: 17.20
+	Hs
		686430 KRT85_HUMAN (1-416): 5.21e-87: 277: 30.17		OTX1_HUMAN (26-120): 1.22e-13: 70.1: 35.79
+	Hs
		280862 KRT37_HUMAN (5-422): 3.78e-65: 218: 28.50		HXA1_HUMAN (10-194): 3.1e-30: 114: 17.20
+	Hs
		686500 KRT35_HUMAN (9-422): 1.39e-72: 238: 27.10		OTX1_HUMAN (26-120): 1.22e-13: 70.1: 35.79
+	Hs
		280858 KRT37_HUMAN (5-422): 3.78e-65: 218: 28.50		OTX1_HUMAN (26-120): 1.22e-13: 70.1: 35.79