HitPredict

Interactor 1: DESM (P17661)
Desmin
Gene: DES

Interactor 2: DUX4 (Q9UBX2)
Double homeobox protein 4 (Double homeobox protein 10)
Gene: DUX4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	26816005
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 470 Hs			1 424
+	Hs
		443864 VIME_HUMAN (28-469): 1.16e-150: 439: 62.19		DUX4_HUMAN (1-424): 1.09e-57: 196: 100.00
+	Hs
		1121887 Q53SB5_HUMAN (1-470): 3.6e-109: 333: 100.00		DUX4_HUMAN (1-424): 1.09e-57: 196: 100.00
+	Hs
		569094 DESM_HUMAN (1-470): 3.6e-109: 333: 100.00		DUX4C_HUMAN (1-374): 2.41e-42: 154: 94.12
+	Hs
		215071 DESM_HUMAN (1-470): 3.6e-109: 333: 100.00		DUX1_HUMAN (1-168): 4.99e-35: 129: 82.14
+	Hs
		569116 DESM_HUMAN (1-470): 3.6e-109: 333: 100.00		DUX5_HUMAN (1-168): 3.99e-31: 119: 82.14