HitPredict

Interactor 1: CEBPB (P17676)
CCAAT/enhancer-binding protein beta (C/EBP beta) (Liver activator protein) (LAP) (Liver-enriched inhibitory protein) (LIP) (Nuclear factor NF-IL6) (Transcription factor 5) (TCF-5)
Gene: CEBPB

Interactor 2: CEBPA (P49715)
CCAAT/enhancer-binding protein alpha (C/EBP alpha)
Gene: CEBPA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.920

The method score is based on:

Property Details
Experiments 15751966, 34189442, 1840554, 30884312, 20102225
Identification Methods pull down, proximity labelling technology, unspecified method, affinity chromatography technology, peptide array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains bZIP_2~bZIP_2
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
and 20 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 345
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024