HitPredict

Interactor 1: HAP4 (P14064)
Transcriptional activator HAP4
Gene: HAP4

Interactor 2: HAP5 (Q02516)
Transcriptional activator HAP5
Gene: HAP5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.90	0.843

The method score is based on:

Property	Details
Experiments	7828851, 11283351, 9372932, 16278450
Identification Methods	two hybrid, comigration in non denaturing gel electrophoresis, two hybrid pooling approach, pull down
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Hap4_Hap_bind~Histone
Common GO terms	GO:0003677 - DNA binding GO:0006109 - regulation of carbohydrate metabolic process GO:0006355 - regulation of DNA-templated transcription GO:0016602 - CCAAT-binding factor complex GO:0043457 - regulation of cellular respiration and 1 others more... GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	0

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Last updated: 11Aug2025