HitPredict

Interactor 1: CEBPB (P17676)
CCAAT/enhancer-binding protein beta (C/EBP beta) (Liver activator protein) (LAP) (Liver-enriched inhibitory protein) (LIP) (Nuclear factor NF-IL6) (Transcription factor 5) (TCF-5)
Gene: CEBPB

Interactor 2: TLE3 (Q04726)
Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3)
Gene: TLE3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30884312, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 345 Hs			1 772
+	Hs
		831248 CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49		TLE3_HUMAN (1-772): 0: 583: 100.00
+	Hs
		547789 ATF2_HUMAN (49-342): 3.06e-41: 152: 17.63		TLE1_HUMAN (1-772): 0: 538: 77.42
+	Mm
		562979 ATF2_MOUSE (49-342): 2.38e-36: 138: 17.31		TLE1_MOUSE (1-772): 1.82e-174: 522: 78.22
+	Dm
		558407 Q9VTE8_DROME (251-333): 2.61e-15: 73.2: 27.06		GROU_DROME (1-772): 4.17e-136: 421: 57.20
+	Hs
		570041 CEBPB_HUMAN (1-345): 1.14e-78: 246: 100.00		TBL1R_HUMAN (571-771): 3.06e-46: 174: 15.07
+	Hs
		570076 CEBPB_HUMAN (1-345): 1.14e-78: 246: 100.00		GBB4_HUMAN (441-646): 3.79e-39: 150: 20.00
+	Hs
		569541 CEBPB_HUMAN (1-345): 1.14e-78: 246: 100.00		GBB1_HUMAN (567-770): 1.63e-38: 148: 17.62
+	Hs
		569504 CEBPB_HUMAN (1-345): 1.14e-78: 246: 100.00		WDR5_HUMAN (284-560): 2.42e-32: 130: 9.12
+	Hs
		831669 CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49		TBL1R_HUMAN (571-771): 3.06e-46: 174: 15.07
+	Hs
		196953 CEBPB_HUMAN (1-345): 1.14e-78: 246: 100.00		PRP4_HUMAN (555-763): 6.48e-12: 70.9: 28.24
+	Hs
		569952 CEBPB_HUMAN (1-345): 1.14e-78: 246: 100.00		SNR40_HUMAN (509-677): 5.35e-09: 60.8: 26.52
+	Mm
		862794 CEBPA_MOUSE (24-345): 2.92e-47: 165: 29.79		WDR5_MOUSE (284-560): 2.42e-32: 130: 9.12
+	Hs
		196976 CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49		PRP4_HUMAN (555-763): 6.48e-12: 70.9: 28.24
+	Mm
		862800 CEBPA_MOUSE (24-345): 2.92e-47: 165: 29.79		GBB2_MOUSE (688-771): 3.6e-14: 76.4: 16.47
+	Mm
		862885 CEBPA_MOUSE (24-345): 2.92e-47: 165: 29.79		PRP4_MOUSE (555-763): 6.75e-12: 70.9: 28.24
+	Hs
		831572 CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49		SNR40_HUMAN (509-677): 5.35e-09: 60.8: 26.52
+	Hs
		547772 ATF2_HUMAN (49-342): 3.06e-41: 152: 17.63		GBB2_HUMAN (688-771): 3.6e-14: 76.4: 16.47