HitPredict

Interactor 1: CEBPB (P17676)
CCAAT/enhancer-binding protein beta (C/EBP beta) (Liver activator protein) (LAP) (Liver-enriched inhibitory protein) (LIP) (Nuclear factor NF-IL6) (Transcription factor 5) (TCF-5)
Gene: CEBPB

Interactor 2: TRIB1 (Q96RU8)
Tribbles homolog 1 (TRB-1) (G-protein-coupled receptor-induced gene 2 protein) (GIG-2) (SKIP1)
Gene: TRIB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.49	0.60	0.545

Property	Details
Experiments	30254053, 17724128
Identification Methods	unspecified method, two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0032496 - response to lipopolysaccharide
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 345 Hs			1 372
+	Mm
		656011 CEBPB_MOUSE (1-345): 1.32e-49: 169: 64.35		TRIB1_MOUSE (1-372): 8.58e-128: 373: 93.82
+	Hs
		547787 ATF2_HUMAN (49-342): 3.06e-41: 152: 17.63		KPCE_HUMAN (11-371): 2.39e-128: 387: 17.32
+	Mm
		862857 CEBPA_MOUSE (24-345): 2.92e-47: 165: 29.79		TRIB1_MOUSE (1-372): 8.58e-128: 373: 93.82
+	Hs
		831614 CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49		TRIB1_HUMAN (1-372): 7.49e-123: 360: 100.00
+	Hs
		1077833 CEBPE_HUMAN (26-345): 1.04e-44: 156: 32.92		TRIB1_HUMAN (1-372): 7.49e-123: 360: 100.00
+	Hs
		831529 CEBPA_HUMAN (24-345): 1.01e-49: 171: 29.49		TRIB2_HUMAN (52-371): 1.1e-115: 341: 60.25
+	Mm
		862856 CEBPA_MOUSE (24-345): 2.92e-47: 165: 29.79		TRIB2_MOUSE (52-371): 6.83e-114: 336: 59.63
+	Hs
		831923 CEBPD_HUMAN (46-344): 1.55e-36: 134: 28.43		TRIB1_HUMAN (1-372): 7.49e-123: 360: 100.00
+	Mm
		987634 ATF4_MOUSE (121-337): 4.38e-27: 110: 18.26		TRIB3_MOUSE (89-360): 9.59e-93: 283: 54.91
+	Hs
		727181 DDIT3_HUMAN (213-332): 7.77e-24: 97.9: 20.33		TRIB3_HUMAN (89-360): 1.98e-86: 267: 51.65
+	Dm
		971936 CEBP_DROME (186-334): 1.62e-22: 99.8: 24.50		TRIB_DROME (107-338): 2.97e-52: 182: 41.54