HitPredict

Interactor 1: HLAG (P17693)
HLA class I histocompatibility antigen, alpha chain G (HLA G antigen) (MHC class I antigen G) [Cleaved into: Soluble HLA class I histocompatibility antigen, alpha chain G (sHLA-G)]
Gene: HLA-G

Interactor 2: HLAF (P30511)
HLA class I histocompatibility antigen, alpha chain F (CDA12) (HLA F antigen) (Leukocyte antigen F) (MHC class I antigen F)
Gene: HLA-F

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~C1-set, C1-set~MHC_I, MHC_I~MHC_I
Common GO terms GO:0000139 - Golgi membrane
GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0002476 - antigen processing and presentation of endogenous peptide antigen via MHC class Ib
GO:0002486 - antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
GO:0002729 - positive regulation of natural killer cell cytokine production
and 14 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 338
Hs

1 346
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024