Interactor 1: TPH1 (P17752)
Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1)
Gene: TPH1
Interactor 2: TPH2 (Q8IWU9)
Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Neuronal tryptophan hydroxylase) (Tryptophan 5-monooxygenase 2)
Gene: TPH2
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 1.00 | 0.665 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Biopterin_H~Biopterin_H |
| Common GO terms | GO:0004510 - tryptophan 5-monooxygenase activity GO:0005506 - iron ion binding GO:0005829 - cytosol GO:0009072 - aromatic amino acid metabolic process GO:0042427 - serotonin biosynthetic process and 1 others more... |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Dd | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
