Interactor 1: ACHB2 (P17787)
Neuronal acetylcholine receptor subunit beta-2
Gene: CHRNB2

Interactor 2: ACHA5 (P30532)
Neuronal acetylcholine receptor subunit alpha-5
Gene: CHRNA5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 33961781, 8663494
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Neur_chan_LBD~Neur_chan_LBD, Neur_chan_LBD~Neur_chan_memb, Neur_chan_memb~Neur_chan_memb
Common GO terms GO:0005886 - plasma membrane
GO:0005892 - acetylcholine-gated channel complex
GO:0007165 - signal transduction
GO:0007271 - synaptic transmission, cholinergic
GO:0015276 - ligand-gated monoatomic ion channel activity
and 8 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 502
Hs

1 468
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024