Interactor 1: PYRG1 (P17812)
CTP synthase 1 (EC 6.3.4.2) (CTP synthetase 1) (UTP--ammonia ligase 1)
Gene: CTPS1

Interactor 2: PYRG1 (P17812)
CTP synthase 1 (EC 6.3.4.2) (CTP synthetase 1) (UTP--ammonia ligase 1)
Gene: CTPS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 25416956, 32296183, unassigned1304
Identification Methods two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CTP_synth_N~CTP_synth_N, CTP_synth_N~GATase, GATase~GATase
Common GO terms GO:0003883 - CTP synthase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006139 - nucleobase-containing compound metabolic process
and 9 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 591
Hs

1 591
+ Hs
+ Hs
+ Dm
+ Zm
+ Sc
+ Sc
+ Sc
+ Ec
+ Cj

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024