Interactor 1: PYRG1 (P17812)
CTP synthase 1 (EC 6.3.4.2) (CTP synthetase 1) (UTP--ammonia ligase 1)
Gene: CTPS1
Interactor 2: PYRG2 (Q9NRF8)
CTP synthase 2 (EC 6.3.4.2) (CTP synthetase 2) (UTP--ammonia ligase 2)
Gene: CTPS2
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.89 | 1.00 | 0.946 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 35271311, 36652389, 28514442, 32296183, 33961781, unassigned1304 |
| Identification Methods | affinity chromatography technology, cross-linking study, two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CTP_synth_N~CTP_synth_N, CTP_synth_N~GATase, GATase~GATase |
| Common GO terms | GO:0003883 - CTP synthase activity GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006241 - CTP biosynthetic process and 4 others more... |
| Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
