HitPredict

Interactor 1: EGLN (P17813)
Endoglin (CD antigen CD105)
Gene: ENG

Interactor 2: TGFR2 (P37173)
TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II)
Gene: TGFBR2

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.696

The method score is based on:

Property Details
Experiments 12015308, 9872992, 15702480, 16785228
Identification Methods affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001569 - branching involved in blood vessel morphogenesis
GO:0001570 - vasculogenesis
GO:0001837 - epithelial to mesenchymal transition
GO:0001947 - heart looping
GO:0003148 - outflow tract septum morphogenesis
and 16 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 658
Hs

1 567
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Last updated: 15 Jul 2024