Interactor 1: EGLN (P17813)
Endoglin (CD antigen CD105)
Gene: ENG

Interactor 2: ACVR1 (Q04771)
Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)
Gene: ACVR1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 9872992
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001569 - branching involved in blood vessel morphogenesis
GO:0005886 - plasma membrane
GO:0007179 - transforming growth factor beta receptor signaling pathway
GO:0030509 - BMP signaling pathway
GO:0042803 - protein homodimerization activity
and 4 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 658
Hs

1 509
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Last updated: 15 Jul 2024