Interactor 1: EGLN (P17813)
Endoglin (CD antigen CD105)
Gene: ENG

Interactor 2: GDF2 (Q9UK05)
Growth/differentiation factor 2 (GDF-2) (Bone morphogenetic protein 9) (BMP-9)
Gene: GDF2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 0.60 0.646

The method score is based on:

Property Details
Experiments 17311849, 28564608
Identification Methods pull down, x-ray crystallography, bio-layer interferometry, molecular sieving
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001569 - branching involved in blood vessel morphogenesis
GO:0001570 - vasculogenesis
GO:0001937 - negative regulation of endothelial cell proliferation
GO:0005615 - extracellular space
GO:0030509 - BMP signaling pathway
and 4 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 658
Hs

1 429
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024