HitPredict

Interactor 1: DDX5 (P17844)
Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5) (RNA helicase p68)
Gene: DDX5

Interactor 2: TYY1 (P25490)
Transcriptional repressor protein YY1 (Delta transcription factor) (INO80 complex subunit S) (NF-E1) (Yin and yang 1) (YY-1)
Gene: YY1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	22210892, 23531880
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II and 1 others more... GO:0046332 - SMAD binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 614 Hs			1 414
+	Hs
		632799 DDX42_HUMAN (16-603): 3.74e-156: 474: 34.09		TYY1_HUMAN (1-414): 1.26e-138: 404: 100.00
+	Hs
		133885 DDX3X_HUMAN (2-556): 9.8e-147: 441: 35.52		TYY1_HUMAN (1-414): 1.26e-138: 404: 100.00
+	Hs
		571457 DDX5_HUMAN (1-614): 0: 624: 100.00		MTF1_HUMAN (351-411): 2.81e-09: 61.2: 45.90
+	Hs
		1060168 DDX17_HUMAN (30-612): 0: 534: 66.83		MTF1_HUMAN (351-411): 2.81e-09: 61.2: 45.90
+	Hs
		134047 DDX3X_HUMAN (2-556): 9.8e-147: 441: 35.52		MTF1_HUMAN (351-411): 2.81e-09: 61.2: 45.90
+	Hs
		181698 DDX3Y_HUMAN (2-556): 1.95e-145: 438: 34.93		MTF1_HUMAN (351-411): 2.81e-09: 61.2: 45.90