HitPredict

Interactor 1: DDX5 (P17844)
Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5) (RNA helicase p68)
Gene: DDX5

Interactor 2: KHDR1 (Q07666)
KH domain-containing, RNA-binding, signal transduction-associated protein 1 (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p21 Ras GTPase-activating protein-associated p62) (p68)
Gene: KHDRBS1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	22365833
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000381 - regulation of alternative mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 3 others more... GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 614 Hs			1 443
+	Hs
		571486 DDX5_HUMAN (1-614): 0: 624: 100.00		KHDR2_HUMAN (99-443): 5.18e-130: 381: 60.62
+	Hs
		1139248 DDX17_HUMAN (30-612): 0: 534: 66.83		KHDR2_HUMAN (99-443): 5.18e-130: 381: 60.62
+	Hs
		571467 DDX5_HUMAN (1-614): 0: 624: 100.00		SF01_HUMAN (82-301): 6.63e-54: 192: 21.33
+	Dm
		580769 DDX17_DROME (2-481): 8.16e-150: 451: 60.87		Q9W255_DROME (59-398): 6.04e-96: 295: 32.35
+	Hs
		1075713 DDX17_HUMAN (30-612): 0: 534: 66.83		SF01_HUMAN (82-301): 6.63e-54: 192: 21.33
+	Hs
		1075665 Q59F66_HUMAN (30-602): 6.42e-176: 518: 66.72		SF01_HUMAN (82-301): 6.63e-54: 192: 21.33
+	Hs
		1075690 DDX42_HUMAN (16-603): 3.74e-156: 474: 34.09		SF01_HUMAN (82-301): 6.63e-54: 192: 21.33
+	Dm
		1180155 Q7K4L8_DROME (45-493): 2.6e-113: 356: 42.58		Q7KNS5_DROME (95-402): 3.32e-100: 307: 37.01