Interactor 1: DDX5 (P17844)
Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5) (RNA helicase p68)
Gene: DDX5

Interactor 2: CHD3 (Q12873)
Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.12) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH)
Gene: CHD3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 28977666, 20676135
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~Helicase_C, Helicase_C~Helicase_C, Helicase_C~SNF2-rel_dom
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003723 - RNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 3 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 614
Hs

1 2000
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+ Dm

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Last updated: 15 Jul 2024