HitPredict

Interactor 1: DDX5 (P17844)
Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5) (RNA helicase p68)
Gene: DDX5

Interactor 2: ROA0 (Q13151)
Heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0)
Gene: HNRNPA0

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	22365833
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 614 Hs			1 305
+	Hs
		571307 DDX5_HUMAN (1-614): 0: 624: 100.00		ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42
+	Hs
		453133 DDX5_HUMAN (1-614): 0: 624: 100.00		ROA1_HUMAN (85-183): 1.84e-26: 108: 33.33
+	Hs
		571368 DDX5_HUMAN (1-614): 0: 624: 100.00		ROA3_HUMAN (89-183): 5.41e-23: 99.3: 34.74
+	Hs
		161959 DDX5_HUMAN (1-614): 0: 624: 100.00		HNRDL_HUMAN (3-88): 1.69e-15: 78.1: 27.91
+	Hs
		453509 DDX17_HUMAN (30-612): 0: 534: 66.83		ROA1_HUMAN (85-183): 1.84e-26: 108: 33.33
+	Dm
		973550 Q9W3M7_DROME (22-596): 1.68e-163: 493: 49.57		RB97D_DROME (2-174): 1.23e-34: 132: 45.67
+	Hs
		1048159 DDX17_HUMAN (30-612): 0: 534: 66.83		HNRPD_HUMAN (3-83): 6.84e-16: 78.8: 28.40
+	Hs
		134018 DDX3X_HUMAN (2-556): 9.8e-147: 441: 35.52		PABP4_HUMAN (5-185): 2.85e-44: 161: 19.67
+	Hs
		133858 DDX3X_HUMAN (2-556): 9.8e-147: 441: 35.52		PABP1_HUMAN (5-186): 8.2e-43: 157: 19.57
+	Hs
		133852 DDX3X_HUMAN (2-556): 9.8e-147: 441: 35.52		ROA1_HUMAN (85-183): 1.84e-26: 108: 33.33