HitPredict

Interactor 1: DDX5 (P17844)
Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5) (RNA helicase p68)
Gene: DDX5

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26725010, 29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol and 1 others more... GO:1990904 - ribonucleoprotein complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 614 Hs			1 582
+	Hs
		1116430 DDX17_HUMAN (30-612): 0: 534: 66.83		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		134068 DDX3X_HUMAN (2-556): 9.8e-147: 441: 35.52		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		181706 DDX3Y_HUMAN (2-556): 1.95e-145: 438: 34.93		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		571585 DDX5_HUMAN (1-614): 0: 624: 100.00		MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42
+	Hs
		1116344 DDX46_HUMAN (50-477): 3.83e-108: 350: 40.68		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Mm
		857351 Q8BTS0_MOUSE (1-614): 0: 617: 97.89		TIA1_MOUSE (120-325): 5.06e-24: 106: 13.94
+	Dm
		1182345 Q7KU78_DROME (20-405): 2.19e-180: 520: 64.77		LAR4_DROME (7-205): 4e-47: 180: 22.39
+	Hs
		571469 DDX5_HUMAN (1-614): 0: 624: 100.00		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Sc
		624057 DBP2_YEAST (3-477): 7.12e-164: 481: 57.65		LHP1_YEAST (7-270): 1.34e-45: 163: 22.74
+	Mm
		857323 DDX17_MOUSE (30-612): 0: 536: 66.67		TIA1_MOUSE (120-325): 5.06e-24: 106: 13.94
+	Hs
		1271680 DDX17_HUMAN (30-612): 0: 534: 66.83		RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84
+	Hs
		1077436 DDX17_HUMAN (30-612): 0: 534: 66.83		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Hs
		134018 DDX3X_HUMAN (2-556): 9.8e-147: 441: 35.52		PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98
+	Hs
		133858 DDX3X_HUMAN (2-556): 9.8e-147: 441: 35.52		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		134095 DDX3X_HUMAN (2-556): 9.8e-147: 441: 35.52		LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32
+	Hs
		134141 DDX3X_HUMAN (2-556): 9.8e-147: 441: 35.52		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Hs
		134091 DDX3X_HUMAN (2-556): 9.8e-147: 441: 35.52		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Dm
		1180159 Q7K4L8_DROME (45-493): 2.6e-113: 356: 42.58		LARP_DROME (38-120): 1.58e-13: 76.1: 35.23