HitPredict

Interactor 1: CHD7 (A2AJK6)
Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7)
Gene: CHD7

Interactor 2: ARI1A (A2BH40)
AT-rich interactive domain-containing protein 1A (ARID domain-containing protein 1A) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A) (Osa homolog 1) (SWI-like protein) (SWI/SNF complex protein p270) (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1)
Gene: Arid1a

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21532573
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0003677 - DNA binding GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling GO:0140658 - ATP-dependent chromatin remodeler activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2986 Mm			1 2283
+	Hs
		146292 CHD7_HUMAN (1-2986): 0: 2602: 94.33		ARI1A_HUMAN (27-2283): 0: 889: 94.52
+	Hs
		124109 CHD7_HUMAN (1-2986): 0: 2602: 94.33		SPT5H_HUMAN (572-796): 1.13e-09: 66.2: 15.35
+	Mm
		57767 SMCA4_MOUSE (222-1594): 0: 886: 23.03		ARI1A_MOUSE (11-2283): 0: 964: 100.00
+	Hs
		146222 CHD4_HUMAN (681-1972): 0: 886: 27.17		ARI1A_HUMAN (27-2283): 0: 889: 94.52
+	Hs
		146185 SMCA4_HUMAN (222-1594): 0: 880: 22.38		ARI1A_HUMAN (27-2283): 0: 889: 94.52
+	Hs
		146206 CHD3_HUMAN (540-1972): 0: 875: 26.69		ARI1A_HUMAN (27-2283): 0: 889: 94.52
+	Mm
		57774 SMCA2_MOUSE (222-1653): 0: 790: 21.73		ARI1A_MOUSE (11-2283): 0: 964: 100.00
+	Mm
		57185 SMCA4_MOUSE (222-1594): 0: 886: 23.03		CHD7_MOUSE (1064-1644): 5.88e-16: 87.1: 12.44
+	Mm
		1111969 SMCA4_MOUSE (222-1594): 0: 886: 23.03		Q9D982_MOUSE (1018-1113): 7.2e-16: 78.4: 33.33
+	Hs
		658710 SMCA1_HUMAN (799-1853): 0: 881: 25.90		ARI1B_HUMAN (1-906): 4.06e-14: 81: 8.71
+	Hs
		847021 SMCA4_HUMAN (222-1594): 0: 880: 22.38		ARI1B_HUMAN (1-906): 4.06e-14: 81: 8.71
+	Mm
		93508 SMCA4_MOUSE (222-1594): 0: 886: 23.03		ARI1B_MOUSE (283-1669): 4.27e-11: 71: 11.28
+	Hs
		146283 CHD8_HUMAN (1-846): 2.02e-09: 65.9: 11.22		ARI1A_HUMAN (27-2283): 0: 889: 94.52
+	Hs
		123941 CHD4_HUMAN (681-1972): 0: 886: 27.17		SPT5H_HUMAN (572-796): 1.13e-09: 66.2: 15.35
+	Hs
		847103 SMCA4_HUMAN (222-1594): 0: 880: 22.38		CHD7_HUMAN (9-406): 1.71e-10: 69: 12.62
+	Hs
		123925 CHD3_HUMAN (540-1972): 0: 875: 26.69		SPT5H_HUMAN (572-796): 1.13e-09: 66.2: 15.35
+	Mm
		1150296 SMCA2_MOUSE (222-1653): 0: 790: 21.73		Q9D982_MOUSE (1018-1113): 7.2e-16: 78.4: 33.33
+	Mm
		93512 SMCA2_MOUSE (222-1653): 0: 790: 21.73		ARI1B_MOUSE (283-1669): 4.27e-11: 71: 11.28
+	Hs
		867130 CHD8_HUMAN (1-846): 2.02e-09: 65.9: 11.22		SC24C_HUMAN (523-830): 1.85e-11: 71.8: 23.01
+	Hs
		1336298 CHD8_HUMAN (1-846): 2.02e-09: 65.9: 11.22		CHD7_HUMAN (9-406): 1.71e-10: 69: 12.62