Interactor 1: XBP1 (P17861)
X-box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5) (TREB-5) [Cleaved into: X-box-binding protein 1, cytoplasmic form; X-box-binding protein 1, luminal form]
Gene: XBP1

Interactor 2: XBP1 (P17861)
X-box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5) (TREB-5) [Cleaved into: X-box-binding protein 1, cytoplasmic form; X-box-binding protein 1, luminal form]
Gene: XBP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.885

The method score is based on:

Property Details
Experiments 23661758, 25239945, 20102225, 12805554
Identification Methods fluorescent resonance energy transfer, anti tag coimmunoprecipitation, peptide array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains bZIP_2~bZIP_2
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000976 - transcription cis-regulatory region binding
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
and 93 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 261
Hs

1 261
+ Hs
+ Hs
+ Nv
+ Hs
+ Dm
+ At
+ At
+ At
+ Mb
+ Ce
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At

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Last updated: 15 Jul 2024