HitPredict

Interactor 1: XBP1 (P17861)
X-box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5) (TREB-5) [Cleaved into: X-box-binding protein 1, cytoplasmic form; X-box-binding protein 1, luminal form]
Gene: XBP1

Interactor 2: ZHANG (Q9NS37)
CREB/ATF bZIP transcription factor (Host cell factor-binding transcription factor Zhangfei) (HCF-binding transcription factor Zhangfei)
Gene: CREBZF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

The method score is based on:

Property	Details
Experiments	23661758, 20102225
Identification Methods	fluorescent resonance energy transfer, peptide array
Interaction Type	direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	bZIP_1~bZIP_2
Common GO terms	GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II and 3 others more... GO:0036500 - ATF6-mediated unfolded protein response GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0090575 - RNA polymerase II transcription regulator complex
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	261
Hs

1	354

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024