HitPredict - High confidence protein-protein interactions

Interactor 1: HS71B (P17879)
Heat shock 70 kDa protein 1B (Heat shock 70 kDa protein 1) (HSP70.1)
Gene: Hspa1b

Interactor 2: HS71A (Q61696)
Heat shock 70 kDa protein 1A (Heat shock 70 kDa protein 3) (HSP70.3) (Hsp68)
Gene: Hspa1a

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	23973223
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HSP70~HSP70
Common GO terms	GO:0002020 - protease binding GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005739 - mitochondrion and 21 others more... GO:0005813 - centrosome GO:0005829 - cytosol GO:0006457 - protein folding GO:0009408 - response to heat GO:0016323 - basolateral plasma membrane GO:0016324 - apical plasma membrane GO:0016887 - ATP hydrolysis activity GO:0031072 - heat shock protein binding GO:0031625 - ubiquitin protein ligase binding GO:0031982 - vesicle GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032991 - protein-containing complex GO:0042026 - protein refolding GO:0044183 - protein folding chaperone GO:0045121 - membrane raft GO:0051059 - NF-kappaB binding GO:0051085 - chaperone cofactor-dependent protein refolding GO:0072562 - blood microparticle GO:0090063 - positive regulation of microtubule nucleation GO:0140662 - ATP-dependent protein folding chaperone GO:1901673 - regulation of mitotic spindle assembly
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1	642
Mm

1	641

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Last updated: 15 Jul 2024