HitPredict

Interactor 1: CHD7 (A2AJK6)
Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7)
Gene: CHD7

Interactor 2: Q60I23 (Q60I23)
SRY (sex determining region Y)-box 2 (Sox2 protein) (Transcriptional factor SOX2)
Gene: Sox2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.51	0.60	0.554

Property	Details
Experiments	21532573
Identification Methods	anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2986 Mm			1 319
+	Hs
		818550 CHD7_HUMAN (1-2986): 0: 2602: 94.33		SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24
+	Hs
		727814 CHD7_HUMAN (1-2986): 0: 2602: 94.33		SOX5_HUMAN (17-129): 1.06e-39: 150: 40.71
+	Hs
		1300971 CHD7_HUMAN (1-2986): 0: 2602: 94.33		CIC_HUMAN (10-274): 1.46e-36: 141: 24.28
+	Hs
		818841 CHD7_HUMAN (1-2986): 0: 2602: 94.33		SOX9_HUMAN (27-262): 3.13e-35: 135: 27.24
+	Hs
		1199209 CHD7_HUMAN (1-2986): 0: 2602: 94.33		PB1_HUMAN (8-232): 6.76e-34: 133: 14.67
+	Hs
		727934 CHD7_HUMAN (1-2986): 0: 2602: 94.33		SOX6_HUMAN (18-202): 1.01e-33: 132: 29.73
+	Hs
		1332326 CHD7_HUMAN (1-2986): 0: 2602: 94.33		SOX17_HUMAN (17-285): 5.22e-31: 122: 26.02
+	Hs
		1311936 CHD7_HUMAN (1-2986): 0: 2602: 94.33		SOX7_HUMAN (2-301): 1.16e-26: 110: 25.71
+	Hs
		881831 CHD7_HUMAN (1-2986): 0: 2602: 94.33		SOX10_HUMAN (27-318): 1.19e-26: 110: 24.35
+	Hs
		818102 CHD9_HUMAN (1-2969): 0: 2063: 45.16		SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24
+	Mm
		1142014 SMCA5_MOUSE (835-1870): 0: 900: 27.16		Q60I23_MOUSE (1-319): 7.44e-64: 206: 100.00
+	Hs
		229339 SMCA5_HUMAN (806-1870): 0: 897: 26.80		SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24
+	Hs
		818056 CHD4_HUMAN (681-1972): 0: 886: 27.17		SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24
+	Hs
		229467 SMCA5_HUMAN (806-1870): 0: 897: 26.80		CIC_HUMAN (10-274): 1.46e-36: 141: 24.28
+	Hs
		229376 SMCA5_HUMAN (806-1870): 0: 897: 26.80		SSRP1_HUMAN (21-210): 1.09e-30: 124: 15.71
+	Hs
		1059704 CHD4_HUMAN (681-1972): 0: 886: 27.17		PB1_HUMAN (8-232): 6.76e-34: 133: 14.67
+	Hs
		229270 SMCA5_HUMAN (806-1870): 0: 897: 26.80		NSD2_HUMAN (1-250): 1.25e-27: 115: 11.83
+	Hs
		996673 CHD4_HUMAN (681-1972): 0: 886: 27.17		SSRP1_HUMAN (21-210): 1.09e-30: 124: 15.71
+	Hs
		331813 CHD4_HUMAN (681-1972): 0: 886: 27.17		NSD2_HUMAN (1-250): 1.25e-27: 115: 11.83
+	Zm
		9144 A0A1D6FIP6_MAIZE (852-1888): 0: 886: 27.64		A0A1D6EUM9_MAIZE (13-131): 8.28e-28: 108: 25.83