Interactor 1: DCR2 (A1ZAW0)
Endoribonuclease Dcr-2 (Protein Dicer-2) (EC 3.1.26.3)
Gene: Dcr-2
Interactor 2: Q9VLW8 (Q9VLW8)
LD06392p (R2D2) (R2d2, isoform B) (R2d2, isoform C)
Gene: r2d2
Species: Drosophila melanogaster
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 0.90 | 0.934 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 14512631, 15035985, 15066284, 15985611, 19644447, 23375501, 25822791, 17715232, 16724105, 19635780, 20037596, 20086050, 28723582, 21245036, 28416567, 28415970, 18454937, 38944040, unassigned4 |
| Identification Methods | affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, ion exchange chromatography, experimental interaction detection |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Dicer_platform~dsrm, dsrm~dsrm, Helicase_C~dsrm, PAZ~dsrm, Ribonuclease_3~dsrm |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016442 - RISC complex GO:0030422 - siRNA processing GO:0035197 - siRNA binding and 3 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
