HitPredict

Interactor 1: LEG3 (P17931)
Galectin-3 (Gal-3) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Galactose-specific lectin 3) (Galactoside-binding protein) (GALBP) (IgE-binding protein) (L-31) (Laminin-binding protein) (Lectin L-29) (Mac-2 antigen)
Gene: LGALS3

Interactor 2: CD166 (Q13740)
CD166 antigen (Activated leukocyte cell adhesion molecule) (CD antigen CD166)
Gene: ALCAM

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	26186194, 28514442, 33961781, 24945728
Identification Methods	affinity chromatography technology, enzyme linked immunosorbent assay, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001772 - immunological synapse GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 250 Hs			1 583
+	Hs
		572314 LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00		MUC18_HUMAN (1-575): 2.5e-74: 251: 20.42
+	Hs
		449258 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		CD166_HUMAN (1-583): 9.66e-116: 357: 100.00
+	Hs
		119364 LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67		CD166_HUMAN (1-583): 9.66e-116: 357: 100.00
+	Hs
		121151 LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11		CD166_HUMAN (1-583): 9.66e-116: 357: 100.00
+	Hs
		1045045 LEG9B_HUMAN (108-249): 5.78e-38: 137: 37.67		CD166_HUMAN (1-583): 9.66e-116: 357: 100.00
+	Hs
		449219 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		MUC18_HUMAN (1-575): 2.5e-74: 251: 20.42
+	Hs
		121126 LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11		MUC18_HUMAN (1-575): 2.5e-74: 251: 20.42
+	Hs
		572445 LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00		CADM1_HUMAN (259-493): 5.61e-20: 94.9: 19.64
+	Hs
		449252 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		PTK7_HUMAN (16-146): 1.62e-10: 66.3: 13.74