HitPredict

Interactor 1: LEG3 (P17931)
Galectin-3 (Gal-3) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Galactose-specific lectin 3) (Galactoside-binding protein) (GALBP) (IgE-binding protein) (L-31) (Laminin-binding protein) (Lectin L-29) (Mac-2 antigen)
Gene: LGALS3

Interactor 2: LAMA4 (Q16363)
Laminin subunit alpha-4 (Laminin-14 subunit alpha) (Laminin-8 subunit alpha) (Laminin-9 subunit alpha)
Gene: LAMA4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0062023 - collagen-containing extracellular matrix GO:0070062 - extracellular exosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 250 Hs			1 1823
+	Hs
		814958 LEG7_HUMAN (115-247): 3.1e-45: 149: 35.04		LAMA4_HUMAN (1-1823): 0: 1125: 100.00
+	Hs
		449272 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		LAMA4_HUMAN (1-1823): 0: 1125: 100.00
+	Hs
		119397 LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67		LAMA4_HUMAN (1-1823): 0: 1125: 100.00
+	Hs
		121163 LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11		LAMA4_HUMAN (1-1823): 0: 1125: 100.00
+	Hs
		572286 LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00		LAMA1_HUMAN (132-341): 2.44e-17: 91.2: 20.00
+	Hs
		502812 LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00		LAMC1_HUMAN (13-132): 1.75e-13: 78.5: 20.93
+	Hs
		433120 LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00		LAMB1_HUMAN (20-118): 1.77e-10: 68.5: 18.42
+	Hs
		449350 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		MEGF9_HUMAN (47-276): 1.61e-20: 100: 31.20
+	Hs
		631056 LEG7_HUMAN (115-247): 3.1e-45: 149: 35.04		LAMA1_HUMAN (132-341): 2.44e-17: 91.2: 20.00
+	Hs
		449299 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		FAT4_HUMAN (169-328): 1.06e-17: 92.8: 14.07
+	Hs
		119179 LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67		LAMA1_HUMAN (132-341): 2.44e-17: 91.2: 20.00
+	Hs
		119112 LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67		LAMC1_HUMAN (13-132): 1.75e-13: 78.5: 20.93
+	Hs
		433129 LEG7_HUMAN (115-247): 3.1e-45: 149: 35.04		LAMB1_HUMAN (20-118): 1.77e-10: 68.5: 18.42
+	Hs
		172634 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		LAMA5_HUMAN (5-95): 2.97e-11: 71.1: 20.00
+	Hs
		433109 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		LAMB1_HUMAN (20-118): 1.77e-10: 68.5: 18.42
+	Hs
		119093 LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67		LAMB1_HUMAN (20-118): 1.77e-10: 68.5: 18.42