HitPredict

Interactor 1: LEG3 (P17931)
Galectin-3 (Gal-3) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Galactose-specific lectin 3) (Galactoside-binding protein) (GALBP) (IgE-binding protein) (L-31) (Laminin-binding protein) (Lectin L-29) (Mac-2 antigen)
Gene: LGALS3

Interactor 2: COL12 (Q5KU26)
Collectin-12 (Collectin placenta protein 1) (CL-P1) (hCL-P1) (Nurse cell scavenger receptor 2) (Scavenger receptor class A member 4) (Scavenger receptor with C-type lectin)
Gene: COLEC12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0005886 - plasma membrane GO:0016020 - membrane GO:0045087 - innate immune response GO:0062023 - collagen-containing extracellular matrix
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 250 Hs			1 742
+	Hs
		814967 LEG7_HUMAN (115-247): 3.1e-45: 149: 35.04		COL12_HUMAN (1-742): 1.19e-100: 327: 100.00
+	Hs
		449283 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		COL12_HUMAN (1-742): 1.19e-100: 327: 100.00
+	Hs
		119407 LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67		COL12_HUMAN (1-742): 1.19e-100: 327: 100.00
+	Hs
		121167 LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11		COL12_HUMAN (1-742): 1.19e-100: 327: 100.00
+	Hs
		572377 LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00		SCAR3_HUMAN (2-555): 1.35e-43: 168: 31.99
+	Hs
		530369 LEG7_HUMAN (115-247): 3.1e-45: 149: 35.04		CSPG2_HUMAN (559-742): 1.91e-45: 178: 25.79
+	Hs
		449171 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		CSPG2_HUMAN (559-742): 1.91e-45: 178: 25.79
+	Hs
		814971 LEG7_HUMAN (115-247): 3.1e-45: 149: 35.04		SCAR3_HUMAN (2-555): 1.35e-43: 168: 31.99