HitPredict

Interactor 1: LEG3 (P17931)
Galectin-3 (Gal-3) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Galactose-specific lectin 3) (Galactoside-binding protein) (GALBP) (IgE-binding protein) (L-31) (Laminin-binding protein) (Lectin L-29) (Mac-2 antigen)
Gene: LGALS3

Interactor 2: LEG9C (Q6DKI2)
Galectin-9C (Gal-9C) (Galectin-9-like protein B)
Gene: LGALS9C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Gal-bind_lectin~Gal-bind_lectin
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0030246 - carbohydrate binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 250 Hs			1 356
+	Hs
		119146 LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00		LEG9_HUMAN (1-356): 3.53e-144: 413: 94.10
+	Hs
		119417 LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67		LEG9C_HUMAN (1-356): 4.7e-148: 423: 100.00
+	Hs
		119401 LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67		LEG9B_HUMAN (1-356): 1.44e-146: 419: 98.88
+	Hs
		119003 LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67		LEG9_HUMAN (1-356): 3.53e-144: 413: 94.10
+	Mm
		139220 LEG9_MOUSE (108-249): 6.6e-40: 142: 38.62		LEG9_MOUSE (1-356): 1.12e-138: 399: 68.82
+	Hs
		119005 LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67		LEG8_HUMAN (1-356): 5.35e-107: 317: 30.19
+	Hs
		121051 LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11		LEG8_HUMAN (1-356): 5.35e-107: 317: 30.19
+	Hs
		572276 LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00		LEG3_HUMAN (4-148): 6.75e-42: 148: 37.50
+	Hs
		449181 LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00		LEG1_HUMAN (235-354): 2.01e-34: 125: 32.00
+	Mm
		555719 LEG3_MOUSE (1-250): 7.86e-83: 250: 77.36		LEG3_MOUSE (4-146): 5.73e-41: 146: 36.00
+	Mm
		1207900 Q8C253_MOUSE (1-250): 6.8e-82: 247: 78.87		Q8C253_MOUSE (4-146): 5.73e-41: 146: 36.00
+	Hs
		814917 LEG7_HUMAN (115-247): 3.1e-45: 149: 35.04		LEG7_HUMAN (225-355): 2.3e-39: 137: 38.52
+	Rn
		292050 GRIFN_RAT (114-248): 1.12e-42: 143: 27.21		GRIFN_RAT (224-355): 9.85e-36: 129: 30.83
+	Hs
		449157 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		LEG1_HUMAN (235-354): 2.01e-34: 125: 32.00
+	Hs
		1355591 PP13_HUMAN (112-249): 2.61e-42: 142: 25.52		PP13_HUMAN (222-354): 6.83e-33: 121: 25.00
+	Hs
		983534 LEG10_HUMAN (114-250): 1.36e-40: 138: 25.00		LEG10_HUMAN (222-353): 3.84e-33: 122: 25.18