HitPredict

Interactor 1: LEG3 (P17931)
Galectin-3 (Gal-3) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Galactose-specific lectin 3) (Galactoside-binding protein) (GALBP) (IgE-binding protein) (L-31) (Laminin-binding protein) (Lectin L-29) (Mac-2 antigen)
Gene: LGALS3

Interactor 2: MRC2 (Q9UBG0)
C-type mannose receptor 2 (C-type lectin domain family 13 member E) (Endocytic receptor 180) (Macrophage mannose receptor 2) (Urokinase-type plasminogen activator receptor-associated protein) (UPAR-associated protein) (Urokinase receptor-associated protein) (CD antigen CD280)
Gene: MRC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane GO:0030246 - carbohydrate binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 250 Hs			1 1479
+	Hs
		449371 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		MRC2_HUMAN (1-1479): 0: 1347: 100.00
+	Hs
		119549 LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67		MRC2_HUMAN (1-1479): 0: 1347: 100.00
+	Hs
		121221 LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11		MRC2_HUMAN (1-1479): 0: 1347: 100.00
+	Hs
		1107985 LEG9B_HUMAN (108-249): 5.78e-38: 137: 37.67		MRC2_HUMAN (1-1479): 0: 1347: 100.00
+	Hs
		572372 LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00		COL12_HUMAN (657-813): 2.94e-29: 128: 21.61
+	Hs
		362790 LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00		FINC_HUMAN (175-234): 6.98e-10: 66.2: 46.67
+	Hs
		540411 LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00		MMP9_HUMAN (180-229): 4.9e-10: 66.2: 52.00
+	Hs
		439224 LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00		MMP2_HUMAN (180-229): 1.58e-09: 64.7: 48.00
+	Hs
		530369 LEG7_HUMAN (115-247): 3.1e-45: 149: 35.04		CSPG2_HUMAN (879-1121): 7.22e-31: 135: 19.77
+	Hs
		449171 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		CSPG2_HUMAN (879-1121): 7.22e-31: 135: 19.77
+	Hs
		814967 LEG7_HUMAN (115-247): 3.1e-45: 149: 35.04		COL12_HUMAN (657-813): 2.94e-29: 128: 21.61
+	Hs
		449283 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		COL12_HUMAN (657-813): 2.94e-29: 128: 21.61
+	Hs
		119407 LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67		COL12_HUMAN (657-813): 2.94e-29: 128: 21.61
+	Hs
		121167 LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11		COL12_HUMAN (657-813): 2.94e-29: 128: 21.61
+	Hs
		276916 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		ATRN_HUMAN (617-828): 8.37e-14: 79.1: 12.60
+	Hs
		362931 LEG7_HUMAN (115-247): 3.1e-45: 149: 35.04		FINC_HUMAN (175-234): 6.98e-10: 66.2: 46.67
+	Hs
		362725 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		FINC_HUMAN (175-234): 6.98e-10: 66.2: 46.67
+	Hs
		119068 LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67		FINC_HUMAN (175-234): 6.98e-10: 66.2: 46.67
+	Hs
		121070 LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11		FINC_HUMAN (175-234): 6.98e-10: 66.2: 46.67
+	Hs
		121099 LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11		MMP9_HUMAN (180-229): 4.9e-10: 66.2: 52.00