HitPredict

Interactor 1: VGFR1 (P17948)
Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)
Gene: FLT1

Interactor 2: ARF4 (P18085)
ADP-ribosylation factor 4
Gene: ARF4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016477 - cell migration
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1338 Hs			1 180
+	Hs
		572614 VGFR1_HUMAN (1-1338): 0: 995: 100.00		ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00
+	Hs
		729257 VGFR3_HUMAN (21-1330): 0: 755: 37.92		ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00
+	Hs
		574612 VGFR3_HUMAN (21-1330): 0: 755: 37.92		ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00
+	Hs
		601491 FGFR2_HUMAN (16-348): 8.87e-56: 211: 11.20		ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00
+	Hs
		574596 FGFR3_HUMAN (1-353): 3.63e-53: 203: 11.78		ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00
+	Hs
		452347 PGFRB_HUMAN (25-560): 1.37e-48: 191: 20.73		ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00
+	Hs
		738190 FLT3_HUMAN (14-570): 5.07e-23: 108: 13.57		ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00
+	Hs
		507840 FGFR1_HUMAN (129-520): 2.91e-36: 150: 12.14		ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00
+	Hs
		507936 FGFR1_HUMAN (129-520): 2.91e-36: 150: 12.14		RAB1A_HUMAN (3-180): 6.71e-68: 207: 22.40
+	Hs
		574595 FGFR4_HUMAN (41-238): 1.53e-27: 122: 11.85		ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00
+	Hs
		574613 FLT3_HUMAN (14-570): 5.07e-23: 108: 13.57		ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00