HitPredict

Interactor 1: VGFR1 (P17948)
Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)
Gene: FLT1

Interactor 2: DYN2 (P50570)
Dynamin-2 (EC 3.6.5.5) (Dynamin 2) (Dynamin II)
Gene: DNM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr
Common GO terms	GO:0005768 - endosome GO:0005886 - plasma membrane GO:0005925 - focal adhesion
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1338 Hs			1 870
+	Hs
		557069 PGFRA_HUMAN (11-666): 1.05e-59: 226: 19.41		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		601480 FGFR2_HUMAN (16-348): 8.87e-56: 211: 11.20		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		609215 FGFR3_HUMAN (1-353): 3.63e-53: 203: 11.78		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		729628 VGFR2_HUMAN (2-438): 9.05e-45: 179: 12.15		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		507913 FGFR1_HUMAN (129-520): 2.91e-36: 150: 12.14		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		601616 FGFR2_HUMAN (16-348): 8.87e-56: 211: 11.20		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		609615 FGFR3_HUMAN (1-353): 3.63e-53: 203: 11.78		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		607921 FGFR4_HUMAN (41-238): 1.53e-27: 122: 11.85		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		508270 FGFR1_HUMAN (129-520): 2.91e-36: 150: 12.14		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		608198 FGFR4_HUMAN (41-238): 1.53e-27: 122: 11.85		DYN3_HUMAN (1-870): 0: 994: 78.41