HitPredict

Interactor 1: VGFR1 (P17948)
Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)
Gene: FLT1

Interactor 2: PRKDC (P78527)
DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)
Gene: PRKDC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1338 Hs			1 4128
+	Hs
		729260 VGFR3_HUMAN (21-1330): 0: 755: 37.92		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		601494 FGFR2_HUMAN (16-348): 8.87e-56: 211: 11.20		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		609246 FGFR3_HUMAN (1-353): 3.63e-53: 203: 11.78		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		452388 PGFRB_HUMAN (25-560): 1.37e-48: 191: 20.73		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		729637 VGFR2_HUMAN (2-438): 9.05e-45: 179: 12.15		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		738194 FLT3_HUMAN (14-570): 5.07e-23: 108: 13.57		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		738299 FLT3_HUMAN (14-570): 5.07e-23: 108: 13.57		TRRAP_HUMAN (2754-4128): 0: 828: 15.88
+	Hs
		452416 PGFRB_HUMAN (25-560): 1.37e-48: 191: 20.73		ATR_HUMAN (3377-4128): 2.05e-122: 438: 19.28