Interactor 1: VGFR1 (P17948)
Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)
Gene: FLT1
Interactor 2: PGBM (P98160)
Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) (Perlecan) (PLC) [Cleaved into: Endorepellin; LG3 peptide]
Gene: HSPG2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.53 | 1.00 | 0.730 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21596751 |
| Identification Methods | far western blotting, pull down, solid phase assay, enzyme linked immunosorbent assay |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | I-set~I-set, I-set~Ig_2, Ig_3~I-set, ig~I-set, Ig_2~ig, Ig_3~ig, Ig_2~Ig_3, Ig_3~Ig_3, Ig_3~Laminin_G_1 |
| Common GO terms | GO:0001525 - angiogenesis GO:0005615 - extracellular space GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0030154 - cell differentiation |
| Homologous interactions | 9 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
