HitPredict

Interactor 1: PDI (P17967)
Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Thioredoxin-related glycoprotein 1)
Gene: PDI1

Interactor 2: PDI (P17967)
Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Thioredoxin-related glycoprotein 1)
Gene: PDI1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.836

The method score is based on:

Property Details
Experiments 18815132, 16413482
Identification Methods x-ray crystallography, affinity chromatography technology, pull down, protein complementation assay
Interaction Type association, physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Thioredoxin~Thioredoxin, Thioredoxin~Thioredoxin_6, Thioredoxin_6~Thioredoxin_6
Common GO terms GO:0003756 - protein disulfide isomerase activity
GO:0005783 - endoplasmic reticulum
GO:0005788 - endoplasmic reticulum lumen
GO:0006457 - protein folding
GO:0009986 - cell surface
and 7 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 522
Sc

1 522
+ Sc
+ Ce
+ Dm
+ Rn
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024