HitPredict

Interactor 1: PDI (P17967)
Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Thioredoxin-related glycoprotein 1)
Gene: PDI1

Interactor 2: ERO1 (Q03103)
Endoplasmic oxidoreductin-1 (EC 1.8.4.-) (Endoplasmic reticulum oxidoreductase protein 1)
Gene: ERO1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 0.60 0.726

The method score is based on:

Property Details
Experiments 10549279, 30880408, 35084835, 20669236, 22412017, 16368681
Identification Methods affinity chromatography technology, pull down, enzymatic study, classical fluorescence spectroscopy
Interaction Type physical association, direct interaction, enzymatic reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0015035 - protein-disulfide reductase activity
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 522
Sc

1 563
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024