HitPredict

Interactor 1: PRS6A (P17980)
26S proteasome regulatory subunit 6A (26S proteasome AAA-ATPase subunit RPT5) (Proteasome 26S subunit ATPase 3) (Proteasome subunit P50) (Tat-binding protein 1) (TBP-1)
Gene: PSMC3

Interactor 2: TBD2B (Q9UPU7)
TBC1 domain family member 2B
Gene: TBC1D2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 439 Hs			1 963
+	Hs
		573075 PRS6A_HUMAN (1-439): 1.23e-136: 401: 100.00		PKHA4_HUMAN (31-494): 3.01e-115: 373: 16.39
+	Hs
		906922 PRS4_HUMAN (32-433): 5.45e-136: 399: 43.60		PKHA4_HUMAN (31-494): 3.01e-115: 373: 16.39
+	Hs
		907156 PRS8_HUMAN (65-437): 1.93e-126: 373: 44.39		PKHA4_HUMAN (31-494): 3.01e-115: 373: 16.39
+	Hs
		798759 PRS6B_HUMAN (8-438): 1.04e-118: 354: 37.59		PKHA4_HUMAN (31-494): 3.01e-115: 373: 16.39
+	Sc
		703762 PRS6A_YEAST (20-439): 2.06e-117: 351: 68.08		GYP5_YEAST (241-962): 1.95e-94: 320: 15.21
+	Hs
		875319 TERA_HUMAN (162-434): 9.21e-77: 256: 35.17		PKHA4_HUMAN (31-494): 3.01e-115: 373: 16.39
+	Hs
		1239605 AFG2A_HUMAN (182-435): 3.65e-68: 234: 35.32		PKHA4_HUMAN (31-494): 3.01e-115: 373: 16.39
+	Hs
		874998 TERA_HUMAN (162-434): 9.21e-77: 256: 35.17		TB10B_HUMAN (294-950): 2.55e-95: 321: 17.02
+	Hs
		875021 TERA_HUMAN (162-434): 9.21e-77: 256: 35.17		TBC9B_HUMAN (524-962): 5.3e-90: 314: 23.18
+	Hs
		875464 TERA_HUMAN (162-434): 9.21e-77: 256: 35.17		RBGP1_HUMAN (573-962): 2.36e-89: 310: 22.08