HitPredict

Interactor 1: TCPA (P17987)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Chaperonin containing T-complex polypeptide 1 subunit 1)
Gene: TCP1

Interactor 2: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31501420, 38280479
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 556 Hs			1 504
+	Hs
		573490 TCPA_HUMAN (1-556): 0: 630: 100.00		SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05
+	Hs
		125246 TCPG_HUMAN (5-550): 0: 593: 33.03		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		808395 TCPG_HUMAN (5-550): 0: 593: 33.03		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		125243 TCPE_HUMAN (4-530): 0: 550: 31.96		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		1306694 TCPH_HUMAN (1-545): 0: 566: 34.84		SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05
+	Hs
		808391 TCPE_HUMAN (4-530): 0: 550: 31.96		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Sc
		760801 TCPG_YEAST (1-538): 0: 552: 29.20		TOM1_YEAST (261-504): 2.18e-46: 176: 11.34
+	Hs
		1306711 TCPH_HUMAN (1-545): 0: 566: 34.84		WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61
+	Sc
		792404 TCPH_YEAST (10-531): 1.74e-87: 282: 35.10		TOM1_YEAST (261-504): 2.18e-46: 176: 11.34