HitPredict

Interactor 1: TCPA (P17987)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Chaperonin containing T-complex polypeptide 1 subunit 1)
Gene: TCP1

Interactor 2: TCPG (P49368)
T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Chaperonin containing T-complex polypeptide 1 subunit 3) (hTRiC5)
Gene: CCT3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.950

The method score is based on:

Property Details
Experiments 28514442, 33961781, 35271311, 35235311, 16085932, 37071682
Identification Methods affinity chromatography technology, cross-linking study, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cpn60_TCP1~Cpn60_TCP1
Common GO terms GO:0002199 - zona pellucida receptor complex
GO:0003723 - RNA binding
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0005832 - chaperonin-containing T-complex
and 15 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 556
Hs

1 545
+ Bt
+ Hs
+ Bt
+ Hs
+ Bt
+ Hs
+ Mm
+ Hs
+ Dm
+ Ph
+ Hs
+ Bt
+ Hs
+ Bt
+ Hs
+ Hs

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Last updated: 15 Jul 2024