HitPredict

Interactor 1: TCPA (P17987)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Chaperonin containing T-complex polypeptide 1 subunit 1)
Gene: TCP1

Interactor 2: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.50	0.599

Property	Details
Experiments	27705803, 33022573, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 556 Hs			1 334
+	Hs
		826601 TCPG_HUMAN (5-550): 0: 593: 33.03		WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00
+	Hs
		903467 TCPH_HUMAN (1-545): 0: 566: 34.84		WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00
+	Hs
		573384 TCPA_HUMAN (1-556): 0: 630: 100.00		POC1B_HUMAN (5-251): 5.05e-84: 263: 27.89
+	Hs
		573451 TCPA_HUMAN (1-556): 0: 630: 100.00		WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83
+	Hs
		792942 TCPG_HUMAN (5-550): 0: 593: 33.03		LIS1_HUMAN (2-289): 1.55e-94: 288: 29.49
+	Hs
		826784 TCPG_HUMAN (5-550): 0: 593: 33.03		POC1B_HUMAN (5-251): 5.05e-84: 263: 27.89
+	Hs
		826854 TCPG_HUMAN (5-550): 0: 593: 33.03		WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83
+	Hs
		573346 TCPA_HUMAN (1-556): 0: 630: 100.00		WDR5B_HUMAN (3-198): 4.87e-59: 194: 30.10
+	Hs
		1306650 TCPH_HUMAN (1-545): 0: 566: 34.84		WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83
+	Hs
		826748 TCPG_HUMAN (5-550): 0: 593: 33.03		WDR5B_HUMAN (3-198): 4.87e-59: 194: 30.10
+	Hs
		1202777 TCPH_HUMAN (1-545): 0: 566: 34.84		WDR5B_HUMAN (3-198): 4.87e-59: 194: 30.10
+	Hs
		573406 TCPA_HUMAN (1-556): 0: 630: 100.00		FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15
+	Hs
		826807 TCPG_HUMAN (5-550): 0: 593: 33.03		FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15
+	Hs
		573371 TCPA_HUMAN (1-556): 0: 630: 100.00		POC1A_HUMAN (10-75): 1.3e-13: 73.1: 22.73
+	Hs
		573412 TCPA_HUMAN (1-556): 0: 630: 100.00		SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29
+	Hs
		196954 TCPA_HUMAN (1-556): 0: 630: 100.00		PRP4_HUMAN (244-333): 1.12e-10: 64.2: 19.39
+	Hs
		826772 TCPG_HUMAN (5-550): 0: 593: 33.03		POC1A_HUMAN (10-75): 1.3e-13: 73.1: 22.73
+	Hs
		196973 TCPG_HUMAN (5-550): 0: 593: 33.03		PRP4_HUMAN (244-333): 1.12e-10: 64.2: 19.39
+	Hs
		1240450 TCPH_HUMAN (1-545): 0: 566: 34.84		POC1A_HUMAN (10-75): 1.3e-13: 73.1: 22.73
+	Hs
		197078 TCPH_HUMAN (1-545): 0: 566: 34.84		PRP4_HUMAN (244-333): 1.12e-10: 64.2: 19.39