HitPredict

Interactor 1: TCPA (P17987)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Chaperonin containing T-complex polypeptide 1 subunit 1)
Gene: TCP1

Interactor 2: BIRC3 (Q13489)
Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin transferase BIRC3) (TNFR2-TRAF-signaling complex protein 1)
Gene: BIRC3

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30948266, 15494311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 556 Hs			1 604
+	Hs
		826648 TCPG_HUMAN (5-550): 0: 593: 33.03		BIRC3_HUMAN (1-604): 0: 676: 100.00
+	Hs
		1036010 TCPH_HUMAN (1-545): 0: 566: 34.84		BIRC3_HUMAN (1-604): 0: 676: 100.00
+	Hs
		821196 TCPE_HUMAN (4-530): 0: 550: 31.96		BIRC3_HUMAN (1-604): 0: 676: 100.00
+	Dm
		520030 TCPA_DROME (1-555): 0: 579: 73.33		DIAP2_DROME (9-100): 4.66e-25: 110: 31.52
+	Hs
		826811 TCPG_HUMAN (5-550): 0: 593: 33.03		MIB2_HUMAN (544-603): 2.9e-10: 65.3: 35.00
+	Dm
		820624 TCPG_DROME (5-551): 0: 546: 29.98		DIAP2_DROME (9-100): 4.66e-25: 110: 31.52
+	Hs
		1284690 TCPH_HUMAN (1-545): 0: 566: 34.84		MIB2_HUMAN (544-603): 2.9e-10: 65.3: 35.00
+	Hs
		821350 TCPE_HUMAN (4-530): 0: 550: 31.96		MIB2_HUMAN (544-603): 2.9e-10: 65.3: 35.00
+	Dm
		1097143 Q9VHL2_DROME (10-532): 1.6e-93: 298: 36.11		DIAP2_DROME (9-100): 4.66e-25: 110: 31.52
+	Dm
		1097181 Q9W392_DROME (14-538): 9.77e-89: 285: 35.22		DIAP2_DROME (9-100): 4.66e-25: 110: 31.52