HitPredict

Interactor 1: TCPA (P17987)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Chaperonin containing T-complex polypeptide 1 subunit 1)
Gene: TCP1

Interactor 2: FBXW8 (Q8N3Y1)
F-box/WD repeat-containing protein 8 (F-box and WD-40 domain-containing protein 8) (F-box only protein 29)
Gene: FBXW8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21946088
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 556 Hs			1 598
+	Hs
		826762 TCPG_HUMAN (5-550): 0: 593: 33.03		FBXW8_HUMAN (1-598): 4.17e-132: 400: 96.17
+	Hs
		573406 TCPA_HUMAN (1-556): 0: 630: 100.00		FBXW7_HUMAN (285-590): 1.43e-81: 272: 13.88
+	Hs
		826807 TCPG_HUMAN (5-550): 0: 593: 33.03		FBXW7_HUMAN (285-590): 1.43e-81: 272: 13.88
+	Hs
		573342 TCPA_HUMAN (1-556): 0: 630: 100.00		WDR86_HUMAN (64-420): 1.44e-55: 194: 13.30
+	Hs
		573346 TCPA_HUMAN (1-556): 0: 630: 100.00		WDR5B_HUMAN (40-372): 8.51e-54: 188: 13.41
+	Hs
		573446 TCPA_HUMAN (1-556): 0: 630: 100.00		TBL1Y_HUMAN (329-589): 8.89e-51: 185: 11.93
+	Hs
		826743 TCPG_HUMAN (5-550): 0: 593: 33.03		WDR86_HUMAN (64-420): 1.44e-55: 194: 13.30
+	Hs
		826748 TCPG_HUMAN (5-550): 0: 593: 33.03		WDR5B_HUMAN (40-372): 8.51e-54: 188: 13.41
+	Hs
		573384 TCPA_HUMAN (1-556): 0: 630: 100.00		POC1B_HUMAN (428-590): 8.43e-39: 150: 15.39
+	Hs
		826848 TCPG_HUMAN (5-550): 0: 593: 33.03		TBL1Y_HUMAN (329-589): 8.89e-51: 185: 11.93
+	Hs
		1198554 TCPH_HUMAN (1-545): 0: 566: 34.84		WDR86_HUMAN (64-420): 1.44e-55: 194: 13.30
+	Hs
		792942 TCPG_HUMAN (5-550): 0: 593: 33.03		LIS1_HUMAN (6-327): 3.89e-44: 164: 11.60
+	Hs
		1202777 TCPH_HUMAN (1-545): 0: 566: 34.84		WDR5B_HUMAN (40-372): 8.51e-54: 188: 13.41
+	Hs
		573201 TCPA_HUMAN (1-556): 0: 630: 100.00		WDR5_HUMAN (463-590): 7.6e-28: 116: 12.69
+	Hs
		826784 TCPG_HUMAN (5-550): 0: 593: 33.03		POC1B_HUMAN (428-590): 8.43e-39: 150: 15.39
+	Hs
		826945 TCPG_HUMAN (5-550): 0: 593: 33.03		FBW1A_HUMAN (421-593): 2.84e-31: 130: 17.22
+	Hs
		573371 TCPA_HUMAN (1-556): 0: 630: 100.00		POC1A_HUMAN (71-262): 1.3e-15: 81.1: 9.95
+	Hs
		826601 TCPG_HUMAN (5-550): 0: 593: 33.03		WDR5_HUMAN (463-590): 7.6e-28: 116: 12.69
+	Hs
		903467 TCPH_HUMAN (1-545): 0: 566: 34.84		WDR5_HUMAN (463-590): 7.6e-28: 116: 12.69
+	Hs
		826772 TCPG_HUMAN (5-550): 0: 593: 33.03		POC1A_HUMAN (71-262): 1.3e-15: 81.1: 9.95