HitPredict

Interactor 1: TCPA (P17987)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Chaperonin containing T-complex polypeptide 1 subunit 1)
Gene: TCP1

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.950

The method score is based on:

Property Details
Experiments 16085932, 28514442, 33961781, 35271311, 35235311, 34349018
Identification Methods affinity chromatography technology, cross-linking study, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cpn60_TCP1~Cpn60_TCP1
Common GO terms GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0005832 - chaperonin-containing T-complex
GO:0005874 - microtubule
GO:0006457 - protein folding
and 13 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 556
Hs

1 543
+ Bt
+ Hs
+ Mm
+ Bt
+ Hs
+ Hs
+ Bt
+ Dm
+ Hs
+ Ph
+ Hs
+ Bt
+ Bt
+ Hs
+ Hs
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024