HitPredict

Interactor 1: TCPA (P17987)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Chaperonin containing T-complex polypeptide 1 subunit 1)
Gene: TCP1

Interactor 2: STRAB (Q9C0K7)
STE20-related kinase adapter protein beta (STRAD beta) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein) (CALS-21) (ILP-interacting protein) (Pseudokinase ALS2CR2)
Gene: STRADB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 32707033
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 556 Hs			1 418
+	Hs
		573132 TCPA_HUMAN (1-556): 0: 630: 100.00		CDK2_HUMAN (55-375): 1.38e-130: 379: 18.69
+	Hs
		414725 TCPA_HUMAN (1-556): 0: 630: 100.00		CDK1_HUMAN (55-374): 1.01e-123: 361: 20.56
+	Hs
		625228 TCPG_HUMAN (5-550): 0: 593: 33.03		CDK2_HUMAN (55-375): 1.38e-130: 379: 18.69
+	Hs
		826872 TCPG_HUMAN (5-550): 0: 593: 33.03		STRAB_HUMAN (1-418): 5.39e-125: 369: 98.33
+	Hs
		573225 TCPA_HUMAN (1-556): 0: 630: 100.00		CDK5_HUMAN (55-375): 1.04e-108: 323: 16.77
+	Hs
		573237 TCPA_HUMAN (1-556): 0: 630: 100.00		STK4_HUMAN (58-373): 3.33e-104: 318: 25.00
+	Hs
		625579 TCPH_HUMAN (1-545): 0: 566: 34.84		CDK2_HUMAN (55-375): 1.38e-130: 379: 18.69
+	Hs
		131548 TCPA_HUMAN (1-556): 0: 630: 100.00		STK25_HUMAN (58-418): 4.28e-101: 308: 25.48
+	Hs
		573550 TCPA_HUMAN (1-556): 0: 630: 100.00		STK24_HUMAN (42-390): 2.33e-100: 307: 25.22
+	Hs
		1306668 TCPH_HUMAN (1-545): 0: 566: 34.84		STRAB_HUMAN (1-418): 5.39e-125: 369: 98.33
+	Hs
		826737 TCPG_HUMAN (5-550): 0: 593: 33.03		STRAA_HUMAN (20-388): 1.16e-113: 341: 46.61
+	Hs
		415042 TCPH_HUMAN (1-545): 0: 566: 34.84		CDK1_HUMAN (55-374): 1.01e-123: 361: 20.56
+	Hs
		826623 TCPG_HUMAN (5-550): 0: 593: 33.03		CDK5_HUMAN (55-375): 1.04e-108: 323: 16.77
+	Hs
		414817 TCPE_HUMAN (4-530): 0: 550: 31.96		CDK1_HUMAN (55-374): 1.01e-123: 361: 20.56
+	Hs
		826636 TCPG_HUMAN (5-550): 0: 593: 33.03		STK4_HUMAN (58-373): 3.33e-104: 318: 25.00
+	Hs
		826963 TCPG_HUMAN (5-550): 0: 593: 33.03		STK24_HUMAN (42-390): 2.33e-100: 307: 25.22
+	Hs
		960322 TCPH_HUMAN (1-545): 0: 566: 34.84		CDK5_HUMAN (55-375): 1.04e-108: 323: 16.77
+	Hs
		1023098 TCPH_HUMAN (1-545): 0: 566: 34.84		STK4_HUMAN (58-373): 3.33e-104: 318: 25.00
+	Hs
		1306764 TCPH_HUMAN (1-545): 0: 566: 34.84		STK24_HUMAN (42-390): 2.33e-100: 307: 25.22
+	Hs
		1306717 TCPH_HUMAN (1-545): 0: 566: 34.84		STK26_HUMAN (58-390): 2.83e-99: 303: 26.13