Interactor 1: PTN1 (P18031)
Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B)
Gene: PTPN1

Interactor 2: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.501

The method score is based on:

Property Details
Experiments 11579209
Identification Methods in-gel kinase assay
Interaction Type phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008286 - insulin receptor signaling pathway
GO:0019899 - enzyme binding
GO:0019901 - protein kinase binding
and 1 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 435
Hs

1 480
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024