Interactor 1: PTN1 (P18031)
Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B)
Gene: PTPN1
Interactor 2: BCAR1 (P56945)
Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas)
Gene: BCAR1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.85 | 0.60 | 0.718 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 8940134, 9407132, 10889023, 15866871, 9418872 |
| Identification Methods | pull down, affinity chromatography technology, anti tag coimmunoprecipitation, phosphatase assay, coimmunoprecipitation, anti bait coimmunoprecipitation, filter binding |
| Interaction Type | direct interaction, physical association, dephosphorylation reaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008286 - insulin receptor signaling pathway GO:0019901 - protein kinase binding |
| Homologous interactions | 13 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
