HitPredict

Interactor 1: PTPRA (P18052)
Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48) (LCA-related phosphatase) (PTPTY-28)
Gene: PTPRA

Interactor 2: PTPRA (P18052)
Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48) (LCA-related phosphatase) (PTPTY-28)
Gene: PTPRA

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.821

The method score is based on:

Property Details
Experiments 10777529, 7518772
Identification Methods two hybrid, pull down, affinity chromatography technology, phosphatase assay
Interaction Type direct interaction, physical association, dephosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Y_phosphatase~Y_phosphatase
Common GO terms GO:0004725 - protein tyrosine phosphatase activity
GO:0005925 - focal adhesion
GO:0007229 - integrin-mediated signaling pathway
GO:0008286 - insulin receptor signaling pathway
GO:0016020 - membrane
and 8 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 829
Mm

1 829
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Last updated: 15 Jul 2024