HitPredict

Interactor 1: PTPRA (P18052)
Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48) (LCA-related phosphatase) (PTPTY-28)
Gene: PTPRA

Interactor 2: PTPRN (Q60673)
Receptor-type tyrosine-protein phosphatase-like N (R-PTP-N) (PTP IA-2) [Cleaved into: ICA512-N-terminal fragment (ICA512-NTF); ICA512-transmembrane fragment (ICA512-TMF); ICA512-cleaved cytosolic fragment (ICA512-CCF)]
Gene: PTPRN

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.80	0.648

Property	Details
Experiments	12364328
Identification Methods	pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Y_phosphatase~Y_phosphatase
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 829 Mm			1 979
+	Hs
		1031991 PTPRS_HUMAN (5-827): 0: 889: 36.84		PTPRN_HUMAN (32-979): 0: 1185: 86.99
+	Mm
		574005 PTPRA_MOUSE (1-829): 0: 1004: 100.00		PTPR2_MOUSE (42-979): 0: 1055: 44.44
+	Mm
		574008 PTPRA_MOUSE (1-829): 0: 1004: 100.00		PTPRD_MOUSE (704-970): 4.28e-104: 359: 36.43
+	Mm
		573997 PTPRA_MOUSE (1-829): 0: 1004: 100.00		PTPRA_MOUSE (705-970): 7.87e-107: 352: 35.96
+	Mm
		56906 PTPRA_MOUSE (1-829): 0: 1004: 100.00		PTPRF_MOUSE (712-970): 3.36e-99: 345: 36.02
+	Mm
		69645 PTPRA_MOUSE (1-829): 0: 1004: 100.00		PTPRS_MOUSE (707-970): 2.31e-98: 342: 36.47
+	Mm
		574002 PTPRA_MOUSE (1-829): 0: 1004: 100.00		PTPRE_MOUSE (685-970): 2.1e-99: 329: 32.99
+	Hs
		576980 PTPRA_HUMAN (1-829): 0: 973: 89.50		PTPRA_HUMAN (705-970): 7.06e-107: 352: 35.96
+	Hs
		576983 PTPRA_HUMAN (1-829): 0: 973: 89.50		PTPRE_HUMAN (685-970): 1.63e-100: 332: 34.13
+	Mm
		574010 PTPRA_MOUSE (1-829): 0: 1004: 100.00		S4R1M0_MOUSE (679-967): 3.98e-72: 262: 28.75
+	Hs
		616971 PTPRS_HUMAN (5-827): 0: 889: 36.84		PTPRD_HUMAN (704-970): 4.09e-104: 359: 36.80
+	Mm
		573998 PTPRA_MOUSE (1-829): 0: 1004: 100.00		PTPRM_MOUSE (687-973): 8.11e-64: 238: 29.73
+	Hs
		1031977 PTPRS_HUMAN (5-827): 0: 889: 36.84		PTPRS_HUMAN (707-970): 4.49e-101: 350: 36.47
+	Hs
		489957 PTPRS_HUMAN (5-827): 0: 889: 36.84		PTPRF_HUMAN (712-970): 3.24e-99: 345: 36.02
+	Mm
		828098 PTPRD_MOUSE (14-827): 0: 890: 37.85		PTPRE_MOUSE (685-970): 2.1e-99: 329: 32.99
+	Mm
		69646 PTPRS_MOUSE (5-827): 0: 887: 36.26		PTPRE_MOUSE (685-970): 2.1e-99: 329: 32.99
+	Hs
		576984 PTPRA_HUMAN (1-829): 0: 973: 89.50		PTPRG_HUMAN (706-975): 1.5e-56: 215: 27.70
+	Mm
		69654 PTPRS_MOUSE (5-827): 0: 887: 36.26		S4R1M0_MOUSE (679-967): 3.98e-72: 262: 28.75